News News

Performance of the Cox-maze IV procedure is associated with improved long-term survival in patients

Date: 2018-11-06
Views: 9

Title: Performance of the Cox-maze IV procedure is associated with improved long-term survival in patients with atrial fibrillation undergoing cardiac surgery.

Release date: Jan. 2018

Author:  Musharbash FN, et al.

Source:  J Thorac Cardiovasc Surg. 2018; 155(1): 159-170.

Abstract: OBJECTIVE: Atrial fibrillation (AF) is associated with an increased mortality risk. The Cox-maze IV procedure (CM4) performed concomitantly with other cardiac procedures has been shown to be effective for restoring sinus rhythm. However, few data have been published on the late survival of patients undergoing a concomitant CM4. METHODS: Patients undergoing cardiac surgery were retrospectively reviewed from 2001 to 2016 (n = 10,859). Patients were stratified into 3 groups: patients with a history of AF receiving a concomitant CM4 (CM4; n = 438), patients with a history of AF unaddressed during surgery (Untreated AF; n = 1510), and patients without AF history (No AF; n = 8911). Propensity score matching was conducted between the CM4 and Untreated AF groups, and between the CM4 and No AF groups. RESULTS: Thirty-day mortality was similar between the matched groups. Kaplan-Meier analysis showed greater survival for CM4 compared to Untreated AF (P = .004). Ten-year survival was 62% for CM4 and 42% for Untreated AF. Adjusted hazard ratio was 0.47 (95% confidence interval, 0.26-0.86, P = .014). No difference in survival was found between CM4 and No AF groups with the Kaplan-Meier analysis (P = .847). Ten-year survival was 63% for CM4 and 55% for No AF. Adjusted hazard ratio was 1.03 (95% confidence interval, 0.51-2.11, P = .929). CONCLUSIONS: For selected patients with a history of AF undergoing cardiac surgery, concomitant CM4 did not add significantly to postoperative morbidity or mortality and was associated with improved late survival compared with patients with untreated AF and a similar survival to patients without a history of AF.


News / Recommend More
2014 - 10 - 28
Release date: May 16, 2017Author: Wang Longde, et al.Source: Chine J Cerebrovasc Dis.2017;14(4):217-224Abstract: The Global Burden of Disease Study 2013 showed that China was one of the global countries with a high exposure to stroke risk factors and about 94% of stroke burden was caused by manageable risk factors. Incidence: Chinese Monitoring Trends and Determinants in Cardiovascular Disease Pro...
2014 - 10 - 28
Release date: July 4, 2017Author: Chen weiweiSource: Chinese Circulation Journal.2017;32(6):521-530Abstract: The prevalence of cardiovascular risk factors in China is arising, which increased the number of patients with cardiovascular diseases. Overall, the morbidity and mortality of cardiovascular disease in China is still on the ascendant phase. By estimation, the number of patients with cardiov...


  • Links
Copyright ©2005 - 2018 Beijing Med-Zenith Medical Scientific Co., Ltd. 互联网药品信息服务资格证书编号:(京)-非经营性-2017-0064